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Motor Neurone Disease

Volume 453: debated on Tuesday 28 November 2006

To ask the Secretary of State for Trade and Industry what projects related to motor neurone disease were funded by the Medical Research Council in each of the last three years; how much each project received; and if he will make a statement. (102398)

The Medical Research Council (MRC) spent £2.0 million, £2.5 million, £1.5 million in the years 2002-03, 2003-04 and 2004-05 respectively on projects related to Motor Neurone Disease. The Projects involved were:

Organisation

Project Title

Project cost (£)

Cardiff University

Mechanisms of striatal function and repair

1,092,348

Imperial College

The neural control of spinal muscles

63,963

Imperial College

The role of WNT-7a in the formation of sensory-motoneuron connections in the spinal cord

55,803

Institute of Neurology

Development of neuroinformatics tools for the integration and interpretation of imaging in the degeneration of the brain and dementia

52,052

Institute of Psychiatry

MRC London Brain Bank for Research on Neurodegenerative Diseases

349,143

Institute of Psychiatry

The role of phosphorylation in neurofiliament function and dysfunction

192,222

King's College London

A population study and genome wide search for susceptibility genes in amyotropic lateral sclerosis

281,539

King's College London

Identifying a new gene for Motor Neurone Disease

37,809

King's College London - KCL

The role of ephrins and Eph receptors in cranial motor neuron migration and axon pathfinding

202,838

King's College London GKT Schools

Neuroregeneration genomics

315,906

The University of Manchester

Neuronal pathways underlying CNS responses to injury and disease

297,668

University College London UCL

Investigations of function and structure in glutamate (NMDA) and glycine receptors, and of disease-causing mutants.

808,639

University College London UCL

Molecular analysis of growth and regeneration in the nervous system

658,503

University of Bristol

Agonist-induced regulation of metabotropic glutamate receptors

140,004

University of Cambridge

Brain repair

481,325

University of Cambridge

Safety and feasibility of neural transplantation in early to moderate Huntington's disease in the UK.

165,917

University of Liverpool

Relating Function to Structure in lonotropic Glutamate Receptors

193,426

University of Oxford

Genetic approaches to understanding lower motor neurone disease

480,434

University of Oxford

An analytic study of functional coupling within and between cortical and subcortical motor structures

90,798