None. As far as licensed medicinal products are concerned, mannitol is available as an intravenous infusion and is a prescription only medicine which means that pharmacists may only dispense it against a prescription issued by an appropriate practitioner. Mannitol is also used widely as an excipient (i.e. an inactive ingredient) by the pharmaceutical industry in the manufacture of other medicinal products.
There are no specific measures in place to prevent illicit use. Adulterants and bulking agents mixed with controlled drugs are not usually controlled where they are not psychoactive themselves or precursors to psychoactive drugs of misuse.
There are no plans for further restrictions on availability. There is an established mechanism to allow proper consideration of making drugs of misuse controlled. The advisory council on the misuse of drugs (the expert body that advises Ministers) is made aware of problems posed by specific drugs, or where they are requested by Ministers to consider a specific drug, they will undertake a detailed assessment of whether or not a substance ought to be controlled and make appropriate recommendations to Ministers.