The Department and the Food Standards Agency have not commissioned or supported research on this topic. The composition of infant formula is harmonised at European Union (EU)-level, and for fluoride reflects the recommendation of the EU Scientific Committee for Food that, on safety and nutritional grounds, no minimum level, but a maximum level of 100 milligrammes of fluoride per 100 kcal, should be set. This advice recognises the potential fluoride intakes of infants from supplements and/or water used to make up the formula.