Acute hepatitis C infection usually occurs without symptoms, and there are no laboratory tests to differentiate between acute (recent), chronic (long-standing) or resolved hepatitis C infection. Therefore, trends in the number of laboratory diagnoses reflect the number of individuals being tested, rather than the incidence of infection, and those infections identified may have been acquired years or even decades earlier.
The rise in the number of laboratory diagnoses of hepatitis C in London is likely to reflect greater awareness of hepatitis C and increased testing of individuals as part of the investigation of liver disease (including abnormal liver function), testing in known risk groups or as part of screening (for example for occupational health reasons).