The Medicines and Healthcare products Regulatory Agency (formally known as the Medicines Control Agency, and previously the Medicines Division of the Department of Health) has been collecting reports of suspected adverse reactions (ADRs) to medicines and vaccines and any deaths associated with them for 43 years via the Yellow Card Scheme. The scheme records information from health care professionals and patients with a suspicion that an ADR may be related to a drug or vaccine, and has been in operation since 1964.