The properties of the group of herbicides to which aminopyralid belongs—pyridine carboxylic acids—have long been recognised. As a result of this, when the Advisory Committee on Pesticides considered the evaluation of aminopyralid in 2005 it concluded that products containing it should carry warnings on their labels that manure that could contain aminopyralid should not be used on susceptible crops, or on land intended for growing such crops, until all plant material had fully decomposed.
The potential of aminopyralid and other pyridine carboxylic acid herbicides to produce the effects observed were taken into account when the Advisory Committee on Pesticides considered this pesticide in 2005. That this group of chemicals can produce these effects has been known since at least the 1980s.