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Creutzfeldt-Jakob Disease

Volume 486: debated on Monday 12 January 2009

To ask the Secretary of State for Health what reports he has received of the prevalence of new variant CJD in the population carrying the MV gene; and what steps he is taking in response to such reports. (246359)

There have been a total of 167 cases of clinical vCJD in the United Kingdom. All of these patients have been of MM genotype. There has been one reported case of sub-clinical vCJD in a person of MV genotype, who died of an unrelated cause without having developed clinical symptoms of vCJD.

In December 2008, BBC Newsnight reported a case of CJD in a patient of MV genotype. As part of a well established system, all known suspect cases of CJD are reviewed and followed up by the National CJD Surveillance Unit in Edinburgh and the National Prion Unit in London. To date, the National CJD Surveillance Unit has not identified a definite or probable case of vCJD in a non-MM genotype individual.

The measures that have been put in place to minimise the risk of person to person transmission of vCJD are appropriate for the whole population, irrespective of the genotype of the patient.