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NHS: Drugs

Volume 491: debated on Wednesday 22 April 2009

To ask the Secretary of State for Health (1) what estimate he has made of the cost of prescribing anti-depressant drugs in (a) North and East Hertfordshire and (b) England in each of the last five years (i) in cash terms and (ii) in 2009-10 prices; (269646)

(2) what the average net ingredient cost was for drugs falling within section 4.3 of the British National Formulary in each of the last five years (a) in cash terms and (b) in 2009-10 prices.

The information requested is in the following table.

Section 4.3 of the British National Formulary: antidepressant drugs, 2003-07

Net ingredient cost for prescription items dispensed in East and North Hertfordshire PCT1, 2 (£000)

Uprated to 2009-10 prices3

Net ingredient cost for prescription items dispensed in England (£000)

Uprated to 2009-10 prices3

Average net ingredient cost per prescription item dispensed in England (£)

Uprated to 2009-10 prices3

2003

n/a

n/a

395,178.0

458,466.2

14.29

16.58

2004

n/a

n/a

400,681.7

452,542.2

13.82

15.61

2005

3,375.1

3,735.4

338,546.7

374,684.0

11.52

12.75

2006

2,891.7

3,115.0

291,511.4

314,023.8

9.39

10.12

2007

2,683.7

2,812.5

276,107.6

289,357.3

8.16

8.55

1 Data based on current primary care trust (PCT) structure. The structure changed in October 2006 when North Hertfordshire and Stevenage PCT, Royston, Buntingford and Bishop’s Stortford PCT, South East Hertfordshire PCT and Welwyn Hatfield PCT were incorporated into the new East and North Hertfordshire PCT.

2 PCT level data supplied by the NHS Prescriptions Service is only held for a rolling 60-month period.

3 Based on HM Treasury gross domestic product deflators.

Source:

Prescription Cost Analysis (PCA) system.

To ask the Secretary of State for Health how many patients (a) were admitted to hospital and (b) died because of an adverse reaction to prescription medication in each of the last 10 years. (269732)

Reports of suspected adverse drug reactions (ADRs) are collected by the Medicines and Healthcare products Regulatory Agency (MHRA) and Commission for Human Medicines (CHM) through the spontaneous reporting scheme; the Yellow Card Scheme. Approximately 20,000-25,000 reports of ADRs are reported to the MHRA/CHM through this scheme each year. The scheme collects ADR reports from across the whole United Kingdom and includes all medicines, including those from prescriptions, over-the-counter or general retail sales. Reports are also received for herbal medicines and other unlicensed medicines.

The following table shows the number of spontaneous UK suspected Adverse Drug Reaction reports received by the MHRA between 1998 and 2008 which (i) had a fatal outcome (ii) resulted in or prolonged hospitalisation.

Year received by MHRA

Number of spontaneous UK suspected ADR reports received

Number of spontaneous UK suspected ADR reports received with a fatal outcome

Number of spontaneous UK suspected ADR reports received which resulted in or prolonged hospitalisation

1998

18,047

520

2,970

1999

18,483

564

3,212

2000

33,147

632

4,060

2001

21,454

648

3,011

2002

17,602

666

3,624

2003

19,215

733

4,380

2004

19,975

859

4,426

2005

21,917

1,015

4,564

2006

22,001

952

4,621

2007

21,761

1,030

4,500

2008

25,424

1,299

4,487

It is important to note that a report of an adverse drug reaction does not necessarily mean that it was caused by the drug. Many factors have to be taken into account in assessing causal relationships including temporal association, the possible contribution of concomitant medication and the underlying disease being treated.